Abstract Background Breast cancer is a heterogeneous disease for which prognosis and treatment strategies are largely governed by the receptor status (estrogen, progesterone and Her2) of the tumor cells.Gene expression profiling of whole breast tumors further stratifies breast cancer into several molecular subtypes which also co-segregate with the
This study investigates the predictive power of sentiment metrics concerning the volatility of tourism-related stocks listed on the Pakistan Stock Exchange (PSX) during recent crises.We employed univariate and multivariate GARCH-family econometric models to analyze daily data collected from March 2020 to April 2023.The data is categorized into two
Cortical-striatal synaptic dysfunction, including enhanced toxic signaling by extrasynaptic N-methyl-d-aspartate receptors (eNMDARs), precedes neurodegeneration in Huntington disease (HD).A previous study showed Activin A, whose transcription is upregulated by calcium influx via synaptic NMDARs, suppresses eNMDAR signaling.Therefore, we examined th
Efforts to obtain non-intrusive measurement of deformations and spatial flow within soil mass prior to the advent of transparent soils have perceptible limitations.The transparent soil is a two-phase medium composed of both the synthetic aggregate and fluid components of identical refractive indices aiming Electric Skillet at attaining transparency